null

SMILES: Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1

InChI Key: InChIKey=XWCDDZAVVYXKCC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50150080 (CHEMBL340895 | [2-(5-Fluoro-benzofuran-7-yloxy)-et...) Show SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1 Show InChI InChI=1S/C21H20F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-5,8,10-13,24-25H,1-2,6-7,9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetine				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150080 (CHEMBL340895 | [2-(5-Fluoro-benzofuran-7-yloxy)-et...) Show SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1 Show InChI InChI=1S/C21H20F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-5,8,10-13,24-25H,1-2,6-7,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligand				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50150080 (CHEMBL340895 | [2-(5-Fluoro-benzofuran-7-yloxy)-et...) Show SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1 Show InChI InChI=1S/C21H20F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-5,8,10-13,24-25H,1-2,6-7,9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cells				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150080 (CHEMBL340895 | [2-(5-Fluoro-benzofuran-7-yloxy)-et...) Show SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1 Show InChI InChI=1S/C21H20F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-5,8,10-13,24-25H,1-2,6-7,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150080 (CHEMBL340895 | [2-(5-Fluoro-benzofuran-7-yloxy)-et...) Show SMILES Fc1ccc2[nH]cc(CCCNCCOc3cc(F)cc4ccoc34)c2c1 Show InChI InChI=1S/C21H20F2N2O2/c22-16-3-4-19-18(11-16)15(13-25-19)2-1-6-24-7-9-26-20-12-17(23)10-14-5-8-27-21(14)20/h3-5,8,10-13,24-25H,1-2,6-7,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Effective concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing human 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair