BDBM50150083 CHEMBL338482::[2-(5-Fluoro-2-methoxy-phenoxy)-ethyl]-[2-(1H-indol-3-yl)-ethyl]-amine

SMILES: COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12

InChI Key: InChIKey=PDGNKMACWXAEOS-UHFFFAOYSA-N

Data: 2 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50150083 (CHEMBL338482 | [2-(5-Fluoro-2-methoxy-phenoxy)-eth...) Show SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H21FN2O2/c1-23-18-7-6-15(20)12-19(18)24-11-10-21-9-8-14-13-22-17-5-3-2-4-16(14)17/h2-7,12-13,21-22H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetine				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150083 (CHEMBL338482 | [2-(5-Fluoro-2-methoxy-phenoxy)-eth...) Show SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H21FN2O2/c1-23-18-7-6-15(20)12-19(18)24-11-10-21-9-8-14-13-22-17-5-3-2-4-16(14)17/h2-7,12-13,21-22H,8-11H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligand				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150083 (CHEMBL338482 | [2-(5-Fluoro-2-methoxy-phenoxy)-eth...) Show SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H21FN2O2/c1-23-18-7-6-15(20)12-19(18)24-11-10-21-9-8-14-13-22-17-5-3-2-4-16(14)17/h2-7,12-13,21-22H,8-11H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cells				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50150083 (CHEMBL338482 | [2-(5-Fluoro-2-methoxy-phenoxy)-eth...) Show SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H21FN2O2/c1-23-18-7-6-15(20)12-19(18)24-11-10-21-9-8-14-13-22-17-5-3-2-4-16(14)17/h2-7,12-13,21-22H,8-11H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing 5-hydroxytryptamine 1A receptor				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50150083 (CHEMBL338482 | [2-(5-Fluoro-2-methoxy-phenoxy)-eth...) Show SMILES COc1ccc(F)cc1OCCNCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H21FN2O2/c1-23-18-7-6-15(20)12-19(18)24-11-10-21-9-8-14-13-22-17-5-3-2-4-16(14)17/h2-7,12-13,21-22H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	249	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cells				J Med Chem 47: 3823-42 (2004) Article DOI: 10.1021/jm0304010 BindingDB Entry DOI: 10.7270/Q2S46RDW
					More data for this Ligand-Target Pair