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SMILES: [O-][N+](=O)c1ccccc1N1CCN(Cc2nc3ccccc3[nH]2)CC1

InChI Key: InChIKey=KEGYYRUXGXROQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150150   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50150150
PNG
(2-[4-(2-Nitro-phenyl)-piperazin-1-ylmethyl]-1H-ben...)
Show SMILES [O-][N+](=O)c1ccccc1N1CCN(Cc2nc3ccccc3[nH]2)CC1
Show InChI InChI=1S/C18H19N5O2/c24-23(25)17-8-4-3-7-16(17)22-11-9-21(10-12-22)13-18-19-14-5-1-2-6-15(14)20-18/h1-8H,9-13H2,(H,19,20)
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 3.90n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assay

J Med Chem 47: 3853-64 (2004)


Article DOI: 10.1021/jm030505a
BindingDB Entry DOI: 10.7270/Q24B3225
More data for this
Ligand-Target Pair