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SMILES: Brc1cc(Br)c2[nH]c(CN3CCN(CC3)c3ccccn3)nc2c1

InChI Key: InChIKey=QXIHXJBCHQNHHK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150155   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50150155
PNG
(4,6-Dibromo-2-(4-pyridin-2-yl-piperazin-1-ylmethyl...)
Show SMILES Brc1cc(Br)c2[nH]c(CN3CCN(CC3)c3ccccn3)nc2c1
Show InChI InChI=1S/C17H17Br2N5/c18-12-9-13(19)17-14(10-12)21-15(22-17)11-23-5-7-24(8-6-23)16-3-1-2-4-20-16/h1-4,9-10H,5-8,11H2,(H,21,22)
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n/an/an/an/a 416n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro EC50 tested on HEK293 cells co-transfected with human Dopamine receptor D4.4 using FLIPR assay

J Med Chem 47: 3853-64 (2004)


Article DOI: 10.1021/jm030505a
BindingDB Entry DOI: 10.7270/Q24B3225
More data for this
Ligand-Target Pair