null

SMILES: Cc1cc(=O)c(Oc2ccc(Br)cc2Cl)c(o1)-c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=DPYLMVIJRWFZIG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50150198 (3-(4-Bromo-2-chloro-phenoxy)-2-(4-methanesulfonyl-...) Show SMILES Cc1cc(=O)c(Oc2ccc(Br)cc2Cl)c(o1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14BrClO5S/c1-11-9-16(22)19(26-17-8-5-13(20)10-15(17)21)18(25-11)12-3-6-14(7-4-12)27(2,23)24/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole blood				J Med Chem 47: 3874-86 (2004) Article DOI: 10.1021/jm049882t BindingDB Entry DOI: 10.7270/Q2HM57WX
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50150198 (3-(4-Bromo-2-chloro-phenoxy)-2-(4-methanesulfonyl-...) Show SMILES Cc1cc(=O)c(Oc2ccc(Br)cc2Cl)c(o1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14BrClO5S/c1-11-9-16(22)19(26-17-8-5-13(20)10-15(17)21)18(25-11)12-3-6-14(7-4-12)27(2,23)24/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Devi Ahilya Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole blood				Bioorg Med Chem Lett 15: 313-20 (2004) Article DOI: 10.1016/j.bmcl.2004.10.077 BindingDB Entry DOI: 10.7270/Q2NZ88VQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50150198 (3-(4-Bromo-2-chloro-phenoxy)-2-(4-methanesulfonyl-...) Show SMILES Cc1cc(=O)c(Oc2ccc(Br)cc2Cl)c(o1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14BrClO5S/c1-11-9-16(22)19(26-17-8-5-13(20)10-15(17)21)18(25-11)12-3-6-14(7-4-12)27(2,23)24/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Devi Ahilya Vishwavidyalaya Curated by ChEMBL					Assay Description Inhibitory concentration for Cyclooxygenase-1 (Prostaglandin G/H synthase 1) in human whole blood				Bioorg Med Chem Lett 15: 313-20 (2004) Article DOI: 10.1016/j.bmcl.2004.10.077 BindingDB Entry DOI: 10.7270/Q2NZ88VQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50150198 (3-(4-Bromo-2-chloro-phenoxy)-2-(4-methanesulfonyl-...) Show SMILES Cc1cc(=O)c(Oc2ccc(Br)cc2Cl)c(o1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14BrClO5S/c1-11-9-16(22)19(26-17-8-5-13(20)10-15(17)21)18(25-11)12-3-6-14(7-4-12)27(2,23)24/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole blood				J Med Chem 47: 3874-86 (2004) Article DOI: 10.1021/jm049882t BindingDB Entry DOI: 10.7270/Q2HM57WX
					More data for this Ligand-Target Pair