BDBM50150292 (S)-1-((R)-2-Hydroxy-3,3-dimethyl-butyryl)-azetidine-2-carboxylic acid 2-aminomethyl-5-chloro-benzylamide::CHEMBL361432
SMILES: CC(C)(C)[C@@H](O)C(=O)N1CC[C@H]1C(=O)NCc1cc(Cl)ccc1CN
InChI Key: InChIKey=OYRFSDDCPNYGHJ-GJZGRUSLSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prothrombin (Homo sapiens (Human)) | BDBM50150292 ((S)-1-((R)-2-Hydroxy-3,3-dimethyl-butyryl)-azetidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition constant against human Thrombin | Bioorg Med Chem Lett 14: 4161-4 (2004) Article DOI: 10.1016/j.bmcl.2004.06.030 BindingDB Entry DOI: 10.7270/Q2833RH3 | |||||||||||
More data for this Ligand-Target Pair |