BDBM50150536 2-(2-Bromo-phenylamino)-4-methyl-pentanoic acid cyanomethyl-amide::CHEMBL184828

SMILES: CC(C)CC(Nc1ccccc1Br)C(=O)NCC#N

InChI Key: InChIKey=NROOIGDKQAVUOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Oryctolagus cuniculus (rabbit))	BDBM50150536 (2-(2-Bromo-phenylamino)-4-methyl-pentanoic acid cy...) Show SMILES CC(C)CC(Nc1ccccc1Br)C(=O)NCC#N Show InChI InChI=1S/C14H18BrN3O/c1-10(2)9-13(14(19)17-8-7-16)18-12-6-4-3-5-11(12)15/h3-6,10,13,18H,8-9H2,1-2H3,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory concentration against humanized rabbit cathepsin K				Bioorg Med Chem Lett 14: 4291-5 (2004) Article DOI: 10.1016/j.bmcl.2004.05.087 BindingDB Entry DOI: 10.7270/Q2765DS1
					More data for this Ligand-Target Pair