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SMILES: CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2cccc(c2)C(F)(F)F)CC1

InChI Key: InChIKey=JAYXOYIRNYUIMZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150556   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 1


(Homo sapiens (Human))		BDBM50150556
PNG
(1-Methyl-4-(3-{4-[3-(3-trifluoromethyl-phenyl)-iso...)
Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cc(no2)-c2cccc(c2)C(F)(F)F)CC1
Show InChI InChI=1S/C24H26F3N3O2/c1-29-11-13-30(14-12-29)10-3-15-31-21-8-6-18(7-9-21)23-17-22(28-32-23)19-4-2-5-20(16-19)24(25,26)27/h2,4-9,16-17H,3,10-15H2,1H3
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand

Bioorg Med Chem Lett 14: 4307-11 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.080
BindingDB Entry DOI: 10.7270/Q23F4P4M
More data for this
Ligand-Target Pair