BindingDB logo
myBDB logout

null

SMILES: CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)CSc3ccncc3)ccc2n1

InChI Key: InChIKey=QUVDEYLFACHOLE-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150704   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50150704
PNG
(CHEMBL186842 | N-[2-(4-Ethyl-piperazin-1-yl)-4-met...)
Show SMILES CCN1CCN(CC1)c1cc(C)c2cc(NC(=O)CSc3ccncc3)ccc2n1
Show InChI InChI=1S/C23H27N5OS/c1-3-27-10-12-28(13-11-27)22-14-17(2)20-15-18(4-5-21(20)26-22)25-23(29)16-30-19-6-8-24-9-7-19/h4-9,14-15H,3,10-13,16H2,1-2H3,(H,25,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.20E+3n/an/an/an/an/an/a



Argenta Discovery Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Melanin-concentrating hormone 1 receptor expressed in CHO cells

J Med Chem 47: 3962-71 (2004)


Article DOI: 10.1021/jm040762v
BindingDB Entry DOI: 10.7270/Q2668CP3
More data for this
Ligand-Target Pair