BDBM50150788 2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-phenol::2,3,5-tribromo-6-(3,5-dibromo-2-hydroxyphenoxy)phenol::CHEMBL148503

SMILES: Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)cc1Br

InChI Key: InChIKey=OBMWDTFRQJRRIM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
12-Lipoxygenase (12-LOX) (Homo sapiens (Human))	BDBM50150788 (2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...) Show SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)cc1Br Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human platelet 12-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50150788 (2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...) Show SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)cc1Br Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Bak binding to Mcl-1 by FRET assay				J Nat Prod 72: 443-9 (2009) Article DOI: 10.1021/np800737z BindingDB Entry DOI: 10.7270/Q2XW4NMD
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50150788 (2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...) Show SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)cc1Br Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 15-lipoxygenase				J Nat Prod 58: 1384-1391 (1995) Article DOI: 10.1021/np50123a008 BindingDB Entry DOI: 10.7270/Q22B8Z26
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50150788 (2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...) Show SMILES Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)cc1Br Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibitory effect on human reticulocyte 15-lipoxygenase				J Med Chem 47: 4060-5 (2004) Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV
					More data for this Ligand-Target Pair