Found 4 hits for monomerid = 50150788 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
12-Lipoxygenase (12-LOX)
(Homo sapiens (Human)) | BDBM50150788
(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibitory effect on human platelet 12-lipoxygenase |
J Med Chem 47: 4060-5 (2004)
Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV |
More data for this Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50150788
(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of Bak binding to Mcl-1 by FRET assay |
J Nat Prod 72: 443-9 (2009)
Article DOI: 10.1021/np800737z BindingDB Entry DOI: 10.7270/Q2XW4NMD |
More data for this Ligand-Target Pair | |
Arachidonate 15-lipoxygenase
(Homo sapiens (Human)) | BDBM50150788
(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of 15-lipoxygenase |
J Nat Prod 58: 1384-1391 (1995)
Article DOI: 10.1021/np50123a008 BindingDB Entry DOI: 10.7270/Q22B8Z26 |
More data for this Ligand-Target Pair | |
Arachidonate 15-lipoxygenase
(Homo sapiens (Human)) | BDBM50150788
(2,3,5-tribromo-6-(3,5-dibromo-2-hydroxy-phenoxy)-p...)Show InChI InChI=1S/C12H5Br5O3/c13-4-1-6(15)10(18)8(2-4)20-12-7(16)3-5(14)9(17)11(12)19/h1-3,18-19H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibitory effect on human reticulocyte 15-lipoxygenase |
J Med Chem 47: 4060-5 (2004)
Article DOI: 10.1021/jm049872s BindingDB Entry DOI: 10.7270/Q2SX6CPV |
More data for this Ligand-Target Pair | |