BDBM50150798 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ((R)-carbamoylmethyl)-amide::CHEMBL185199

SMILES: Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NCC(N)=O

InChI Key: InChIKey=BNLSEGXVNPKOOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50150798 (2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propi...) Show SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NCC(N)=O Show InChI InChI=1S/C23H28N4O4/c1-13-7-17(28)8-14(2)18(13)10-19(24)23(31)27-12-16-6-4-3-5-15(16)9-20(27)22(30)26-11-21(25)29/h3-8,19-20,28H,9-12,24H2,1-2H3,(H2,25,29)(H,26,30)	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Inhibition of Opioid receptor mu 1 in guinea pig ileum assay				J Med Chem 47: 4066-71 (2004) Article DOI: 10.1021/jm040033f BindingDB Entry DOI: 10.7270/Q2P55N09
					More data for this Ligand-Target Pair