BDBM50150825 CHEMBL3774804
SMILES: CC(C)COc1ccc(cc1)S(=O)(=O)Nc1ccc2n(C)c(=O)n(C)c2c1
InChI Key: InChIKey=YAGHBCRCIAJKTI-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription intermediary factor 1-alpha (Homo sapiens (Human)) | BDBM50150825 (CHEMBL3774804) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas MD Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins... | J Med Chem 59: 1440-54 (2016) BindingDB Entry DOI: 10.7270/Q26975F4 | |||||||||||
More data for this Ligand-Target Pair |