BDBM50150885 6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)-pyridin-2-ylamine::CHEMBL364188

SMILES: CCc1cc(c(OC)cc1CN(C)C)-c1cccc(N)n1

InChI Key: InChIKey=PUBVCUKUEHJWSF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50150885 (6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)...) Show SMILES CCc1cc(c(OC)cc1CN(C)C)-c1cccc(N)n1 Show InChI InChI=1S/C17H23N3O/c1-5-12-9-14(15-7-6-8-17(18)19-15)16(21-4)10-13(12)11-20(2)3/h6-10H,5,11H2,1-4H3,(H2,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against neuronal nitric oxide synthase in human				Bioorg Med Chem Lett 14: 4511-4 (2004) Article DOI: 10.1016/j.bmcl.2004.06.043 BindingDB Entry DOI: 10.7270/Q28S4QP6
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50150885 (6-(4-Dimethylaminomethyl-5-ethyl-2-methoxy-phenyl)...) Show SMILES CCc1cc(c(OC)cc1CN(C)C)-c1cccc(N)n1 Show InChI InChI=1S/C17H23N3O/c1-5-12-9-14(15-7-6-8-17(18)19-15)16(21-4)10-13(12)11-20(2)3/h6-10H,5,11H2,1-4H3,(H2,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase in human				Bioorg Med Chem Lett 14: 4511-4 (2004) Article DOI: 10.1016/j.bmcl.2004.06.043 BindingDB Entry DOI: 10.7270/Q28S4QP6
					More data for this Ligand-Target Pair