BDBM50151005 (S)-1-((S)-7-Methoxy-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-pyrrolidine-2-carbonitrile::(S)-1-((S)-7-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL186566

SMILES: COc1ccc2C[C@H](NCc2c1)C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=GLOOONPUAUYPHG-ZFWWWQNUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50151005 ((S)-1-((S)-7-Methoxy-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccc2C[C@H](NCc2c1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H19N3O2/c1-21-14-5-4-11-8-15(18-10-12(11)7-14)16(20)19-6-2-3-13(19)9-17/h4-5,7,13,15,18H,2-3,6,8,10H2,1H3/t13-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50151005 ((S)-1-((S)-7-Methoxy-1,2,3,4-tetrahydro-isoquinoli...) Show SMILES COc1ccc2C[C@H](NCc2c1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H19N3O2/c1-21-14-5-4-11-8-15(18-10-12(11)7-14)16(20)19-6-2-3-13(19)9-17/h4-5,7,13,15,18H,2-3,6,8,10H2,1H3/t13-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against dipeptidyl-peptidase IV				J Med Chem 47: 4135-41 (2004) Article DOI: 10.1021/jm030628v BindingDB Entry DOI: 10.7270/Q2902380
					More data for this Ligand-Target Pair