BDBM50151154 CHEMBL3770896

SMILES: CCCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1

InChI Key: InChIKey=YMCWHDFPVFAVEE-ZDUSSCGKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50151154 (CHEMBL3770896) Show SMILES CCCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 |r| Show InChI InChI=1S/C15H20N2O3/c1-2-3-4-11-5-7-12(8-6-11)10-20-15(19)17-13-9-16-14(13)18/h5-8,13H,2-4,9-10H2,1H3,(H,16,18)(H,17,19)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Italian Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...				Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM50151154 (CHEMBL3770896) Show SMILES CCCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 |r| Show InChI InChI=1S/C15H20N2O3/c1-2-3-4-11-5-7-12(8-6-11)10-20-15(19)17-13-9-16-14(13)18/h5-8,13H,2-4,9-10H2,1H3,(H,16,18)(H,17,19)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Italian Institute of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysis				Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX
					More data for this Ligand-Target Pair
Acid ceramidase (AC) (Homo sapiens (Human))	BDBM50151154 (CHEMBL3770896) Show SMILES CCCCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1 |r| Show InChI InChI=1S/C15H20N2O3/c1-2-3-4-11-5-7-12(8-6-11)10-20-15(19)17-13-9-16-14(13)18/h5-8,13H,2-4,9-10H2,1H3,(H,16,18)(H,17,19)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Italian Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human acid ceramidase by UPLC/MS analysis				Eur J Med Chem 111: 138-59 (2016) BindingDB Entry DOI: 10.7270/Q2GQ70MX
					More data for this Ligand-Target Pair