BDBM50151359 4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine::CHEMBL359611

SMILES: Cc1ccc(nc1)-c1nc(N)sc1-c1ccnc2ccccc12

InChI Key: InChIKey=USWZUNDOUGZOOF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151359 (4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...) Show SMILES Cc1ccc(nc1)-c1nc(N)sc1-c1ccnc2ccccc12 Show InChI InChI=1S/C18H14N4S/c1-11-6-7-15(21-10-11)16-17(23-18(19)22-16)13-8-9-20-14-5-3-2-4-12(13)14/h2-10H,1H3,(H2,19,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151359 (4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-...) Show SMILES Cc1ccc(nc1)-c1nc(N)sc1-c1ccnc2ccccc12 Show InChI InChI=1S/C18H14N4S/c1-11-6-7-15(21-10-11)16-17(23-18(19)22-16)13-8-9-20-14-5-3-2-4-12(13)14/h2-10H,1H3,(H2,19,22)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity for Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair