BDBM50151561 2-Amino-4-{5-[(Z)-cyclohexylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-benzamide::CHEMBL363118

SMILES: Cn1nc(s\c1=N/C1CCCCC1)-c1ccc(C(N)=O)c(N)c1

InChI Key: InChIKey=AYCNLFPKXSXOKW-MNDPQUGUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50151561 (2-Amino-4-{5-[(Z)-cyclohexylimino]-4-methyl-4,5-di...) Show SMILES Cn1nc(s\c1=N/C1CCCCC1)-c1ccc(C(N)=O)c(N)c1 Show InChI InChI=1S/C16H21N5OS/c1-21-16(19-11-5-3-2-4-6-11)23-15(20-21)10-7-8-12(14(18)22)13(17)9-10/h7-9,11H,2-6,17H2,1H3,(H2,18,22)/b19-16-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 14: 4607-13 (2004) Article DOI: 10.1016/j.bmcl.2004.07.008 BindingDB Entry DOI: 10.7270/Q2377855
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50151561 (2-Amino-4-{5-[(Z)-cyclohexylimino]-4-methyl-4,5-di...) Show SMILES Cn1nc(s\c1=N/C1CCCCC1)-c1ccc(C(N)=O)c(N)c1 Show InChI InChI=1S/C16H21N5OS/c1-21-16(19-11-5-3-2-4-6-11)23-15(20-21)10-7-8-12(14(18)22)13(17)9-10/h7-9,11H,2-6,17H2,1H3,(H2,18,22)/b19-16-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 14: 4607-13 (2004) Article DOI: 10.1016/j.bmcl.2004.07.008 BindingDB Entry DOI: 10.7270/Q2377855
					More data for this Ligand-Target Pair