BDBM50151622 6'',8''-dichlorospiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL184791

SMILES: Clc1cc(Cl)c2NC(=O)NC3(CCCCC3)c2c1

InChI Key: InChIKey=ZDCNWTVHBBCDAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM50151622 (6'',8''-dichlorospiro[cyclohexane-1,4''-(1'',2'',3...) Show SMILES Clc1cc(Cl)c2NC(=O)NC3(CCCCC3)c2c1 Show InChI InChI=1S/C13H14Cl2N2O/c14-8-6-9-11(10(15)7-8)16-12(18)17-13(9)4-2-1-3-5-13/h6-7H,1-5H2,(H2,16,17,18)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 14: 4623-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.011 BindingDB Entry DOI: 10.7270/Q2ZG6RQX
					More data for this Ligand-Target Pair