BDBM50151938 4-{1-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-phenol::CHEMBL186405

SMILES: COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc(O)cc3)c2c1

InChI Key: InChIKey=SSHZMSUPVHRNNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151938 (4-{1-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-1,2,3,6-t...) Show SMILES COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc(O)cc3)c2c1 |c:16| Show InChI InChI=1S/C24H28N2O2/c1-28-22-9-10-24-23(16-22)20(17-25-24)4-2-3-13-26-14-11-19(12-15-26)18-5-7-21(27)8-6-18/h5-11,16-17,25,27H,2-4,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair