BDBM50151945 3-{4-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL185938

SMILES: NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1

InChI Key: InChIKey=TYPRYKUBSLGLEL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50151945 (3-{4-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-butyl...) Show SMILES NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 Show InChI InChI=1S/C24H29N5O2/c25-23(30)17-4-7-20(8-5-17)29-13-11-28(12-14-29)10-2-1-3-19-16-27-22-9-6-18(24(26)31)15-21(19)22/h4-9,15-16,27H,1-3,10-14H2,(H2,25,30)(H2,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>850	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranes				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50151945 (3-{4-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-butyl...) Show SMILES NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 Show InChI InChI=1S/C24H29N5O2/c25-23(30)17-4-7-20(8-5-17)29-13-11-28(12-14-29)10-2-1-3-19-16-27-22-9-6-18(24(26)31)15-21(19)22/h4-9,15-16,27H,1-3,10-14H2,(H2,25,30)(H2,26,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Inhibition of 8-OH DPAT bindign to rat hydroxytryptamine 1A receptor expressed in CHO cells				J Med Chem 47: 4677-83 (2004) Article DOI: 10.1021/jm040792y BindingDB Entry DOI: 10.7270/Q28S4PCR
					More data for this Ligand-Target Pair