BDBM50152038 3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-propyl-butyl)-1,2,3,7-tetrahydro-purin-6-one::CHEMBL184938

SMILES: CCCC(CCC)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=DTMWOWMZYRXNDY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 2 (Homo sapiens (Human))	BDBM50152038 (3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...) Show SMILES CCCC(CCC)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H28Cl2N4O/c1-5-8-15(9-6-2)27-18(7-3)24-20-19(27)21(28)25(4)13-26(20)17-11-10-14(22)12-16(17)23/h10-12,15H,5-9,13H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]- sauvagine binding to corticotropin releasing factor receptor 2 of porcine choroid plexus				J Med Chem 47: 4741-54 (2004) Article DOI: 10.1021/jm049787k BindingDB Entry DOI: 10.7270/Q21C1WBB
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat))	BDBM50152038 (3-(2,4-Dichloro-phenyl)-8-ethyl-1-methyl-7-(1-prop...) Show SMILES CCCC(CCC)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H28Cl2N4O/c1-5-8-15(9-6-2)27-18(7-3)24-20-19(27)21(28)25(4)13-26(20)17-11-10-14(22)12-16(17)23/h10-12,15H,5-9,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor				J Med Chem 47: 4741-54 (2004) Article DOI: 10.1021/jm049787k BindingDB Entry DOI: 10.7270/Q21C1WBB
					More data for this Ligand-Target Pair