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SMILES: Cc1cnc(N)nc1NCC(C)(C)C

InChI Key: InChIKey=AZTUNUDWMRRGIW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxidized purine nucleoside triphosphate hydrolase


(Homo sapiens (Human))		BDBM50152130
PNG
(CHEMBL3780613)
Show SMILES Cc1cnc(N)nc1NCC(C)(C)C
Show InChI InChI=1S/C10H18N4/c1-7-5-12-9(11)14-8(7)13-6-10(2,3)4/h5H,6H2,1-4H3,(H3,11,12,13,14)
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Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



MD Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assay

Bioorg Med Chem Lett 26: 1503-7 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.026
BindingDB Entry DOI: 10.7270/Q20K2BF6
More data for this
Ligand-Target Pair