BDBM50152149 CHEMBL3780961

SMILES: [I-].Cc1c2c(cc3cc[n+](C)cc13)n(C)c1ccccc21

InChI Key: InChIKey=ABLCIRFOALJFEI-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase II alpha (HuTopoIIα) (Homo sapiens (Human))	BDBM50152149 (CHEMBL3780961) Show SMILES [I-].Cc1c2c(cc3cc[n+](C)cc13)n(C)c1ccccc21 Show InChI InChI=1S/C18H17N2.HI/c1-12-15-11-19(2)9-8-13(15)10-17-18(12)14-6-4-5-7-16(14)20(17)3;/h4-11H,1-3H3;1H/q+1;/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human DNA topoisomerase 2alpha expressed in topoisomerase1 deficient Saccharomyces cerevisiae JEL1 assessed as inhibition o...				Bioorg Med Chem Lett 26: 1809-12 (2016) BindingDB Entry DOI: 10.7270/Q2MC91WG
					More data for this Ligand-Target Pair