null

SMILES: COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(nc3)-c3ccccc3)c(cnc2cc1OCCCN1CCCCC1)C#N

InChI Key: InChIKey=UXHUNXDZZALRBJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152378 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(nc3)-c3ccccc3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C35H39N7O2S/c1-43-32-21-29-31(22-33(32)44-20-8-15-40-13-6-3-7-14-40)37-24-27(23-36)34(29)41-16-18-42(19-17-41)35(45)39-28-11-12-30(38-25-28)26-9-4-2-5-10-26/h2,4-5,9-12,21-22,24-25H,3,6-8,13-20H2,1H3,(H,39,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152378 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(nc3)-c3ccccc3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C35H39N7O2S/c1-43-32-21-29-31(22-33(32)44-20-8-15-40-13-6-3-7-14-40)37-24-27(23-36)34(29)41-16-18-42(19-17-41)35(45)39-28-11-12-30(38-25-28)26-9-4-2-5-10-26/h2,4-5,9-12,21-22,24-25H,3,6-8,13-20H2,1H3,(H,39,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair