null

SMILES: COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(C)n1

InChI Key: InChIKey=KOYCHYABQCWZAV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152395 (4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(C)n1 Show InChI InChI=1S/C27H37N7O2S2/c1-20-31-21(18-38-20)17-28-27(37)34-12-10-33(11-13-34)26-22-15-24(35-2)25(16-23(22)29-19-30-26)36-14-6-9-32-7-4-3-5-8-32/h15-16,18-19H,3-14,17H2,1-2H3,(H,28,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152395 (4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(C)n1 Show InChI InChI=1S/C27H37N7O2S2/c1-20-31-21(18-38-20)17-28-27(37)34-12-10-33(11-13-34)26-22-15-24(35-2)25(16-23(22)29-19-30-26)36-14-6-9-32-7-4-3-5-8-32/h15-16,18-19H,3-14,17H2,1-2H3,(H,28,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair