BDBM50152404 8-(4-Methyl-cyclohexyloxy)-quinolin-2-ylamine::CHEMBL184573

SMILES: CC1CCC(CC1)Oc1cccc2ccc(N)nc12

InChI Key: InChIKey=OQURIDUAVDCPLT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50152404 (8-(4-Methyl-cyclohexyloxy)-quinolin-2-ylamine | CH...) Show SMILES CC1CCC(CC1)Oc1cccc2ccc(N)nc12 |(-5.22,-4.11,;-3.86,-3.36,;-3.85,-1.83,;-2.53,-1.05,;-1.2,-1.83,;-1.2,-3.36,;-2.53,-4.14,;.14,-1.05,;.14,.48,;-1.2,1.25,;-1.2,2.8,;.14,3.58,;1.45,2.8,;2.8,3.58,;4.11,2.81,;4.14,1.27,;5.48,.51,;2.81,.51,;1.45,1.25,)| Show InChI InChI=1S/C16H20N2O/c1-11-5-8-13(9-6-11)19-14-4-2-3-12-7-10-15(17)18-16(12)14/h2-4,7,10-11,13H,5-6,8-9H2,1H3,(H2,17,18)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4873-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.032 BindingDB Entry DOI: 10.7270/Q2QV3KZG
					More data for this Ligand-Target Pair