BDBM50152448 8-(2-Methylsulfanyl-ethoxy)-quinolin-2-ylamine::CHEMBL184086

SMILES: CSCCOc1cccc2ccc(N)nc12

InChI Key: InChIKey=JZRCCMGLVXGYEF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50152448 (8-(2-Methylsulfanyl-ethoxy)-quinolin-2-ylamine | C...) Show SMILES CSCCOc1cccc2ccc(N)nc12 Show InChI InChI=1S/C12H14N2OS/c1-16-8-7-15-10-4-2-3-9-5-6-11(13)14-12(9)10/h2-6H,7-8H2,1H3,(H2,13,14)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4873-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.032 BindingDB Entry DOI: 10.7270/Q2QV3KZG
					More data for this Ligand-Target Pair