BDBM50152470 CHEMBL364210::N-[3-(2-Amino-quinolin-8-yloxy)-propyl]-3-trifluoromethoxy-benzamide

SMILES: Nc1ccc2cccc(OCCCNC(=O)c3cccc(OC(F)(F)F)c3)c2n1

InChI Key: InChIKey=FSOINXNNUNLJJD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50152470 (CHEMBL364210 | N-[3-(2-Amino-quinolin-8-yloxy)-pro...) Show SMILES Nc1ccc2cccc(OCCCNC(=O)c3cccc(OC(F)(F)F)c3)c2n1 Show InChI InChI=1S/C20H18F3N3O3/c21-20(22,23)29-15-6-1-5-14(12-15)19(27)25-10-3-11-28-16-7-2-4-13-8-9-17(24)26-18(13)16/h1-2,4-9,12H,3,10-11H2,(H2,24,26)(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
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