BDBM50152471 CHEMBL363464::N-[3-(2-{[5-(3-Chloro-phenyl)-furan-2-ylmethyl]-amino}-quinolin-8-yloxy)-propyl]-3-cyano-benzamide

SMILES: Clc1cccc(c1)-c1ccc(CNc2ccc3cccc(OCCCNC(=O)c4cccc(c4)C#N)c3n2)o1

InChI Key: InChIKey=ZIBVEEKTPIMGAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50152471 (CHEMBL363464 | N-[3-(2-{[5-(3-Chloro-phenyl)-furan...) Show SMILES Clc1cccc(c1)-c1ccc(CNc2ccc3cccc(OCCCNC(=O)c4cccc(c4)C#N)c3n2)o1 Show InChI InChI=1S/C31H25ClN4O3/c32-25-9-2-7-23(18-25)27-13-12-26(39-27)20-35-29-14-11-22-6-3-10-28(30(22)36-29)38-16-4-15-34-31(37)24-8-1-5-21(17-24)19-33/h1-3,5-14,17-18H,4,15-16,20H2,(H,34,37)(H,35,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
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