BDBM50152486 3-Chloro-N-[3-(2-{[5-(2-chloro-phenyl)-furan-2-ylmethyl]-amino}-quinolin-8-yloxy)-propyl]-benzamide::CHEMBL362768

SMILES: Clc1cccc(c1)C(=O)NCCCOc1cccc2ccc(NCc3ccc(o3)-c3ccccc3Cl)nc12

InChI Key: InChIKey=LABXCLZSSDAEEV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50152486 (3-Chloro-N-[3-(2-{[5-(2-chloro-phenyl)-furan-2-ylm...) Show SMILES Clc1cccc(c1)C(=O)NCCCOc1cccc2ccc(NCc3ccc(o3)-c3ccccc3Cl)nc12 Show InChI InChI=1S/C30H25Cl2N3O3/c31-22-8-3-7-21(18-22)30(36)33-16-5-17-37-27-11-4-6-20-12-15-28(35-29(20)27)34-19-23-13-14-26(38-23)24-9-1-2-10-25(24)32/h1-4,6-15,18H,5,16-17,19H2,(H,33,36)(H,34,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes				Bioorg Med Chem Lett 14: 4879-82 (2004) Article DOI: 10.1016/j.bmcl.2004.07.034 BindingDB Entry DOI: 10.7270/Q2M32V61
					More data for this Ligand-Target Pair