BDBM50152567 2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-butyric acid::CHEMBL367585

SMILES: OC(=O)C(=O)CC(=O)c1ccc(s1)C(F)(F)F

InChI Key: InChIKey=LCARJFQPJXGRFO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50152567 (2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...) Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)C(F)(F)F Show InChI InChI=1S/C9H5F3O4S/c10-9(11,12)7-2-1-6(17-7)4(13)3-5(14)8(15)16/h1-2H,3H2,(H,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50152567 (2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...) Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)C(F)(F)F Show InChI InChI=1S/C9H5F3O4S/c10-9(11,12)7-2-1-6(17-7)4(13)3-5(14)8(15)16/h1-2H,3H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Flap endonuclease-1				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair