BDBM50152683 CHEMBL3781674

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1

InChI Key: InChIKey=XFVRBLHJVSIYPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50152683 (CHEMBL3781674) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C41H37ClF2N4O5/c1-25-15-19-47(20-16-25)18-5-21-52-37-24-32-30(23-36(37)51-2)34(14-17-45-32)53-35-13-10-27(22-31(35)44)46-40(49)38-39(42)29-6-3-4-7-33(29)48(41(38)50)28-11-8-26(43)9-12-28/h3-4,6-14,17,22-25H,5,15-16,18-21H2,1-2H3,(H,46,49)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1794-8 (2016) BindingDB Entry DOI: 10.7270/Q2TT4ST4
					More data for this Ligand-Target Pair