BDBM50152745 CHEMBL3780730

SMILES: [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2

InChI Key: InChIKey=TWHZOAJMVSHZKC-ROUUACIJSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152745 (CHEMBL3780730) Show SMILES [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2 |r| Show InChI InChI=1S/C23H22N6O/c1-30-21-10-6-5-9-20(21)27-13-18-11-17(27)14-28(18)22-19-12-26-29(23(19)25-15-24-22)16-7-3-2-4-8-16/h2-10,12,15,17-18H,11,13-14H2,1H3/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 2 (Homo sapiens (Human))	BDBM50152745 (CHEMBL3780730) Show SMILES [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2 |r| Show InChI InChI=1S/C23H22N6O/c1-30-21-10-6-5-9-20(21)27-13-18-11-17(27)14-28(18)22-19-12-26-29(23(19)25-15-24-22)16-7-3-2-4-8-16/h2-10,12,15,17-18H,11,13-14H2,1H3/t17-,18-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 3 (Homo sapiens (Human))	BDBM50152745 (CHEMBL3780730) Show SMILES [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2 |r| Show InChI InChI=1S/C23H22N6O/c1-30-21-10-6-5-9-20(21)27-13-18-11-17(27)14-28(18)22-19-12-26-29(23(19)25-15-24-22)16-7-3-2-4-8-16/h2-10,12,15,17-18H,11,13-14H2,1H3/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...				Bioorg Med Chem Lett 26: 1732-7 (2016) BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair