BDBM50153055 CHEMBL3781691
SMILES: Cn1[nH]c2ccc(cc2c1=O)-c1ccnc(c1)C(Cc1ccccc1)NC(=O)[C@H]1CC[C@H](CN)CC1
InChI Key: InChIKey=HZDUYNOJLIIRJV-DDLDZWDOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor XI (Homo sapiens (Human)) | BDBM50153055 (CHEMBL3781691) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company Curated by ChEMBL | Assay Description Competitive inhibition of human coagulation factor 11a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten eq... | Bioorg Med Chem 24: 2257-72 (2016) BindingDB Entry DOI: 10.7270/Q2DN46X0 | |||||||||||
More data for this Ligand-Target Pair |