null

SMILES: O=c1[nH]cnc2c(CN3CCN(CC3)c3ccccc3)nccc12

InChI Key: InChIKey=RLKIMBNWOBEMJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50153120 (CHEMBL3775295) Show SMILES O=c1[nH]cnc2c(CN3CCN(CC3)c3ccccc3)nccc12 Show InChI InChI=1S/C18H19N5O/c24-18-15-6-7-19-16(17(15)20-13-21-18)12-22-8-10-23(11-9-22)14-4-2-1-3-5-14/h1-7,13H,8-12H2,(H,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1388-409 (2016) Article DOI: 10.1021/acs.jmedchem.5b01635 BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Homo sapiens (Human))	BDBM50153120 (CHEMBL3775295) Show SMILES O=c1[nH]cnc2c(CN3CCN(CC3)c3ccccc3)nccc12 Show InChI InChI=1S/C18H19N5O/c24-18-15-6-7-19-16(17(15)20-13-21-18)12-22-8-10-23(11-9-22)14-4-2-1-3-5-14/h1-7,13H,8-12H2,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1388-409 (2016) Article DOI: 10.1021/acs.jmedchem.5b01635 BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Homo sapiens (Human))	BDBM50153120 (CHEMBL3775295) Show SMILES O=c1[nH]cnc2c(CN3CCN(CC3)c3ccccc3)nccc12 Show InChI InChI=1S/C18H19N5O/c24-18-15-6-7-19-16(17(15)20-13-21-18)12-22-8-10-23(11-9-22)14-4-2-1-3-5-14/h1-7,13H,8-12H2,(H,20,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 1388-409 (2016) Article DOI: 10.1021/acs.jmedchem.5b01635 BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4B (Homo sapiens (Human))	BDBM50153120 (CHEMBL3775295) Show SMILES O=c1[nH]cnc2c(CN3CCN(CC3)c3ccccc3)nccc12 Show InChI InChI=1S/C18H19N5O/c24-18-15-6-7-19-16(17(15)20-13-21-18)12-22-8-10-23(11-9-22)14-4-2-1-3-5-14/h1-7,13H,8-12H2,(H,20,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 1388-409 (2016) Article DOI: 10.1021/acs.jmedchem.5b01635 BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair