BDBM50153128 1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL184451

SMILES: O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1

InChI Key: InChIKey=DSAFTNAGTDWVPT-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50153128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50153128 (1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H31N3O2S/c24-26(25)21-16-17-8-6-7-11-20(17)23(26)19-12-14-22(15-13-19)18-9-4-2-1-3-5-10-18/h6-8,11,18-19,21H,1-5,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]nociceptin binding to human Opioid receptor like 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50153128 (1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H31N3O2S/c24-26(25)21-16-17-8-6-7-11-20(17)23(26)19-12-14-22(15-13-19)18-9-4-2-1-3-5-10-18/h6-8,11,18-19,21H,1-5,9-10,12-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50153128 (1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H31N3O2S/c24-26(25)21-16-17-8-6-7-11-20(17)23(26)19-12-14-22(15-13-19)18-9-4-2-1-3-5-10-18/h6-8,11,18-19,21H,1-5,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50153128 (1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H31N3O2S/c24-26(25)21-16-17-8-6-7-11-20(17)23(26)19-12-14-22(15-13-19)18-9-4-2-1-3-5-10-18/h6-8,11,18-19,21H,1-5,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50153128 (1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C20H31N3O2S/c24-26(25)21-16-17-8-6-7-11-20(17)23(26)19-12-14-22(15-13-19)18-9-4-2-1-3-5-10-18/h6-8,11,18-19,21H,1-5,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair