Found 6 hits for monomerid = 50153129 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]nociceptin binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153129
(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CC1)C1CCC2CCCCC2C1 Show InChI InChI=1S/C22H33N3O2S/c26-28(27)23-16-19-7-3-4-8-22(19)25(28)20-11-13-24(14-12-20)21-10-9-17-5-1-2-6-18(17)15-21/h3-4,7-8,17-18,20-21,23H,1-2,5-6,9-16H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.48E+3 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |