null

SMILES: COc1cccc(c1)N1CCN(CC(=O)Nc2cccc(C)c2)CC1

InChI Key: InChIKey=NPFOWGQVCMDCCC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153265 (2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...) Show SMILES COc1cccc(c1)N1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C20H25N3O2/c1-16-5-3-6-17(13-16)21-20(24)15-22-9-11-23(12-10-22)18-7-4-8-19(14-18)25-2/h3-8,13-14H,9-12,15H2,1-2H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-6b binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153265 (2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...) Show SMILES COc1cccc(c1)N1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C20H25N3O2/c1-16-5-3-6-17(13-16)21-20(24)15-22-9-11-23(12-10-22)18-7-4-8-19(14-18)25-2/h3-8,13-14H,9-12,15H2,1-2H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-spiperone binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153265 (2-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...) Show SMILES COc1cccc(c1)N1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C20H25N3O2/c1-16-5-3-6-17(13-16)21-20(24)15-22-9-11-23(12-10-22)18-7-4-8-19(14-18)25-2/h3-8,13-14H,9-12,15H2,1-2H3,(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity was calculated in calcium flux assay using HEK-293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair