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SMILES: CCOC(=O)c1c(C)n(Cc2cccc(c2)[N+]([O-])=O)c2ccc(OCCCN3CCCCC3)cc12

InChI Key: InChIKey=DXEBAOZMRXLJPT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153269   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein NorA


(Staphylococcus aureus)		BDBM50153269
PNG
(CHEMBL3775575)
Show SMILES CCOC(=O)c1c(C)n(Cc2cccc(c2)[N+]([O-])=O)c2ccc(OCCCN3CCCCC3)cc12
Show InChI InChI=1S/C27H33N3O5/c1-3-34-27(31)26-20(2)29(19-21-9-7-10-22(17-21)30(32)33)25-12-11-23(18-24(25)26)35-16-8-15-28-13-5-4-6-14-28/h7,9-12,17-18H,3-6,8,13-16,19H2,1-2H3
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KEGG

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PC cid
PC sid
UniChem

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PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



University of Perugia

Curated by ChEMBL


Assay Description
Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...

J Med Chem 59: 867-91 (2016)


BindingDB Entry DOI: 10.7270/Q28W3G57
More data for this
Ligand-Target Pair