BDBM50153279 CHEMBL3775483

SMILES: CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCN3CCOCC3)cc12

InChI Key: InChIKey=NPCIVSNUMDPXDA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Quinolone resistance protein norA (Staphylococcus aureus)	BDBM50153279 (CHEMBL3775483) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCCCN3CCOCC3)cc12 Show InChI InChI=1S/C26H32N2O4/c1-3-31-26(29)25-20(2)28(19-21-8-5-4-6-9-21)24-11-10-22(18-23(24)25)32-15-7-12-27-13-16-30-17-14-27/h4-6,8-11,18H,3,7,12-17,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair