BDBM50153339 CHEMBL3775431

SMILES: OC(=O)c1ccncc1NC(=O)Cc1ccccc1

InChI Key: InChIKey=BFYFJTWJGYZODA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4D (Homo sapiens (Human))	BDBM50153339 (CHEMBL3775431) Show SMILES OC(=O)c1ccncc1NC(=O)Cc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(8-10-4-2-1-3-5-10)16-12-9-15-7-6-11(12)14(18)19/h1-7,9H,8H2,(H,16,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectromet...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50153339 (CHEMBL3775431) Show SMILES OC(=O)c1ccncc1NC(=O)Cc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(8-10-4-2-1-3-5-10)16-12-9-15-7-6-11(12)14(18)19/h1-7,9H,8H2,(H,16,17)(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation ...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50153339 (CHEMBL3775431) Show SMILES OC(=O)c1ccncc1NC(=O)Cc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(8-10-4-2-1-3-5-10)16-12-9-15-7-6-11(12)14(18)19/h1-7,9H,8H2,(H,16,17)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153339 (CHEMBL3775431) Show SMILES OC(=O)c1ccncc1NC(=O)Cc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(8-10-4-2-1-3-5-10)16-12-9-15-7-6-11(12)14(18)19/h1-7,9H,8H2,(H,16,17)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair