BDBM50153342 CHEMBL3774863

SMILES: OC(=O)c1ccncc1NC(c1ccccc1)c1ccccc1

InChI Key: InChIKey=KWAMEUZLBKUQHQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153342 (CHEMBL3774863) Show SMILES OC(=O)c1ccncc1NC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-19(23)16-11-12-20-13-17(16)21-18(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-13,18,21H,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair