BDBM50153567 3-Benzo[1,3]dioxol-5-yl-3-{[1-(3-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl-propionyl)-piperidine-4-carbonyl]-amino}-propionic acid::CHEMBL183981

SMILES: OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1

InChI Key: InChIKey=YKDPBQLUFJZRDN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50153567 (3-Benzo[1,3]dioxol-5-yl-3-{[1-(3-5,6,7,8-tetrahydr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O6/c32-24(8-6-20-5-3-17-2-1-11-28-26(17)29-20)31-12-9-18(10-13-31)27(35)30-21(15-25(33)34)19-4-7-22-23(14-19)37-16-36-22/h3-5,7,14,18,21H,1-2,6,8-13,15-16H2,(H,28,29)(H,30,35)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153567 (3-Benzo[1,3]dioxol-5-yl-3-{[1-(3-5,6,7,8-tetrahydr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O6/c32-24(8-6-20-5-3-17-2-1-11-28-26(17)29-20)31-12-9-18(10-13-31)27(35)30-21(15-25(33)34)19-4-7-22-23(14-19)37-16-36-22/h3-5,7,14,18,21H,1-2,6,8-13,15-16H2,(H,28,29)(H,30,35)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair