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SMILES: CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc(C(=O)CC(C)C)c1O

InChI Key: InChIKey=RWJQFJBJUPTMBH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153747   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50153747
PNG
(1-(2-Hydroxy-3-propyl-4-{4-[4-(2H-tetrazol-5-yl)-p...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc(C(=O)CC(C)C)c1O
Show InChI InChI=1S/C25H32N4O4/c1-4-7-21-23(13-12-20(24(21)31)22(30)16-17(2)3)33-15-6-5-14-32-19-10-8-18(9-11-19)25-26-28-29-27-25/h8-13,17,31H,4-7,14-16H2,1-3H3,(H,26,27,28,29)
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Article
PubMed
n/an/an/an/a 421n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay

Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair