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SMILES: CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(Br)c1O

InChI Key: InChIKey=WQSWSCFDPJRFHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153751   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50153751
PNG
(1-(3-Bromo-2-hydroxy-4-{4-[4-(2H-tetrazol-5-yl)-ph...)
Show SMILES CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(Br)c1O
Show InChI InChI=1S/C19H19BrN4O4/c1-12(25)15-8-9-16(17(20)18(15)26)28-11-3-2-10-27-14-6-4-13(5-7-14)19-21-23-24-22-19/h4-9,26H,2-3,10-11H2,1H3,(H,21,22,23,24)
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Article
PubMed
n/an/an/an/a 878n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay

Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair