null

SMILES: N#Cc1ccc(Cn2cncc2CNCc2ccc(C#N)c(c2)-c2cccc3ccccc23)cc1

InChI Key: InChIKey=SSDLNWPTNYTTQB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153774 (4-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methylamin...) Show SMILES N#Cc1ccc(Cn2cncc2CNCc2ccc(C#N)c(c2)-c2cccc3ccccc23)cc1 Show InChI InChI=1S/C30H23N5/c31-15-22-8-10-23(11-9-22)20-35-21-34-19-27(35)18-33-17-24-12-13-26(16-32)30(14-24)29-7-3-5-25-4-1-2-6-28(25)29/h1-14,19,21,33H,17-18,20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50153774 (4-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methylamin...) Show SMILES N#Cc1ccc(Cn2cncc2CNCc2ccc(C#N)c(c2)-c2cccc3ccccc23)cc1 Show InChI InChI=1S/C30H23N5/c31-15-22-8-10-23(11-9-22)20-35-21-34-19-27(35)18-33-17-24-12-13-26(16-32)30(14-24)29-7-3-5-25-4-1-2-6-28(25)29/h1-14,19,21,33H,17-18,20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine farnesyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair