BDBM50153784 3-(benzo[d][1,3]dioxol-4-yl)-4-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)methyl)benzonitrile::3-Benzo[1,3]dioxol-4-yl-4-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-benzonitrile::CHEMBL363041

SMILES: N#Cc1ccc(Cn2cncc2COCc2ccc(cc2-c2cccc3OCOc23)C#N)cc1

InChI Key: InChIKey=KUKOQVKXENRBFD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50153784 (3-(benzo[d][1,3]dioxol-4-yl)-4-(((1-(4-cyanobenzyl...) Show SMILES N#Cc1ccc(Cn2cncc2COCc2ccc(cc2-c2cccc3OCOc23)C#N)cc1 Show InChI InChI=1S/C27H20N4O3/c28-11-19-4-6-20(7-5-19)14-31-17-30-13-23(31)16-32-15-22-9-8-21(12-29)10-25(22)24-2-1-3-26-27(24)34-18-33-26/h1-10,13,17H,14-16,18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine farnesyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair