BDBM50153830 CHEMBL187378::N-[5-(3-Dimethylamino-benzoylamino)-2-methyl-phenyl]-3,4-diethoxy-benzamide

SMILES: CCOc1ccc(cc1OCC)C(=O)Nc1cc(NC(=O)c2cccc(c2)N(C)C)ccc1C

InChI Key: InChIKey=UKHDJGQTAYNMOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50153830 (CHEMBL187378 | N-[5-(3-Dimethylamino-benzoylamino)...) Show SMILES CCOc1ccc(cc1OCC)C(=O)Nc1cc(NC(=O)c2cccc(c2)N(C)C)ccc1C Show InChI InChI=1S/C27H31N3O4/c1-6-33-24-14-12-20(16-25(24)34-7-2)27(32)29-23-17-21(13-11-18(23)3)28-26(31)19-9-8-10-22(15-19)30(4)5/h8-17H,6-7H2,1-5H3,(H,28,31)(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Concentration required to inhibit human mitogen activated protein kinase p38 activity				Bioorg Med Chem Lett 14: 5383-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.006 BindingDB Entry DOI: 10.7270/Q28G8K57
					More data for this Ligand-Target Pair