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SMILES: Cc1ccc(NC(=O)c2cccc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2ccncc2)cc1

InChI Key: InChIKey=KJHOKACGVDIVGB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153840   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50153840
PNG
(4-methyl-1-[3-(1,4-oxazinan-4-yl)phenylcarboxamido...)
Show SMILES Cc1ccc(NC(=O)c2cccc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2ccncc2)cc1
Show InChI InChI=1S/C31H30N4O4/c1-22-5-8-26(33-31(37)25-3-2-4-27(19-25)35-15-17-38-18-16-35)20-29(22)34-30(36)24-6-9-28(10-7-24)39-21-23-11-13-32-14-12-23/h2-14,19-20H,15-18,21H2,1H3,(H,33,37)(H,34,36)
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n/an/a 20n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Concentration required to inhibit human mitogen activated protein kinase p38 activity

Bioorg Med Chem Lett 14: 5383-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.006
BindingDB Entry DOI: 10.7270/Q28G8K57
More data for this
Ligand-Target Pair